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NEW QUESTION: 1
Which of the following is true regarding extent of absorption of drugs?
A. Drugs which are too hydrophilic are not soluble enough to cross the water layer adjacent to the cell
B. P-glycoprotein is an efflux transporter which is present in the enterocytes and it enhances the absorption of drug
C. Drugs which are too lipophilic cannot cross the lipid cell membrane
D. After oral ingestion of drugs, the absorption of drug may be incomplete
E. Grape juice activates P-glycoprotein leading to substantial inhibition of absorption of drugs
Answer: D
Explanation:
Explanation
It is not necessary that all the drugs get completely absorbed after oral administration. Most of them are incompletely absorbed. The extent of absorption varies from 5 to less than 100 % with oral ingestion of drugs.
Drugs which are too hydrophilic like atenolol are incompletely absorbed because the drug cannot cross the lipid membrane due to high hydrophilic nature of the drug. Similarly, drugs which are too lipophilic like acyclovir are not soluble enough to cross the water layer adjacent to the cell. P-glycoprotein is an efflux transporter which is present in the enterocytes and it inhibits absorption of drug. It is also known as export transporter or reverse transporter. It has many drugs as its substrate. Grape juice in fact inhibits P-glycoprotein in the intestine thereby decreasing the efflux of drug from the cells by P-glycoprotein. Thus ingestion of grape juice may lead to significantly increased absorption of the drug.

NEW QUESTION: 2
Refer to the exhibit.

You are configuring the S1 switch for the switch port that connects to the client computer. Which configuration blocks users on the port from using more than 6 Mbps of traffic and marks the traffic for a class of service of 1?
A)

B)

C)

D)

A. Exhibit C
B. Exhibit B
C. Exhibit D
D. Exhibit A
Answer: D
Explanation:
Only option A specified that the exceed and violate actions are set to drop for traffic over the CIR of 6 Mbps, and is also configured to set all traffic with a COS of 1 using the "set cos1" command.

NEW QUESTION: 3
Which of the following describes dynamically switching from one cellular tower to the next without dropping connectivity in cellular and WiFi networks?
A. Bouncing
B. 3-way handshake
C. Roaming
D. Failover
Answer: C

NEW QUESTION: 4
Click the Exhibit button.

Which two statements are true about the route shown in the exhibit? (Choose two.)
A. The route is currently hidden.
B. The route is currently active.
C. The route is currently being damped.
D. The route has an unreachable next-hop.
Answer: A,C
Explanation:
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